منابع مشابه
Genetic markers in glaucoma.
A number of genetic polymorphisms have been investigated in Negro and Caucasoid patients with glaucoma and the results compared with data obtained on healthy controls. A sample of 61 Negro patients was not significantly different from a sample of 238 controls with respect to 18 red cell and serum protein systems; no association between glaucoma and any of these systems could be demonstrated. Th...
متن کاملBlood groups as genetic markers in glaucoma.
A series of 474 mixed cases of glaucoma was assessed to determine whether there were any genetic differences between different types of glaucoma. A careful distinction was made between chronic open angle glaucoma (COAG), acute and chronic angle closure glaucoma, ocular hypertension, low tension glaucoma, patients with large cup disc ratios, and various types of secondary glaucoma including pseu...
متن کاملGlutathione s-transferase M1 and T1 genetic polymorphisms in Iranian patients with glaucoma
Objective(s):Glaucoma is the second leading cause of blindness and it is related to oxidative stress based on numerous studies. Glutathione S-transferases (GSTs) are members of multigenic family, which have important role in cells as an antioxidant. In the present study, we examined the polymorphism of GSTT1 and GSTM1 deletion genotypes (T0M1, T1M0, and T0M0) in 100 Glaucoma patients (41with pr...
متن کاملGenetic Epidemiology of Glaucoma
Purpose. The genetic etiology of primary open-angle glaucoma (POAG) is still largely unknown, because of its complexity and disparities in its classification. We aimed to determine the genetic contribution to various early, continuous markers of POAG by assessing the heritability of intraocular pressure (IOP), retinal nerve fiber layer (RNFL) thickness, and neuroretinal rim and optic disc param...
متن کاملGenetic etiologies of glaucoma.
Glaucoma can be inherited as a mendelian autosomal-dominant or autosomal-recessive trait, or as a complex multifactorial trait. Genetic approaches have helped define the underlying molecular events responsible for some mendelian forms of the disease and have identified the chromosome locations of genes that are likely to contribute to common complex forms. Future directions include the discover...
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ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 1980
ISSN: 0007-1161
DOI: 10.1136/bjo.64.4.227